Spinal interneurons specialized for flexion reflex:
Some spinal interneurons (example at right) are activated at short latency during fictive flexion reflex (limb withdrawal; A), but inhibited during fictive scratching (B) and fictive swimming (C). These interneurons (colored and black circles) were all found in the dorsal horn (D), in contrast to most T neurons (white circles) and most other scratch-activated interneurons (gray circles). (Int, interneuron; HF and KE, hip flexor and knee extensor motor nerves, respectively; Stim., stimulation.)
(Adapted from Berkowitz, J. Neurosci. 27:4634-4641, 2007.)
Strong interactions between scratch and swim spinal cord networks |
Hyperpolarization of scratch-specialized neurons during swim |
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T neurons, a new
morphological & physiological class of spinal interneurons
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Rhythmic activity of interneurons during two types of scratching |
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Rhythmic activity of interneurons during left and right motor rhythms |