ZOO 5903 Sect 001   Bioinformatics: Applications,  3 hour
MW 10:30 - 11:45  NH122 (Nielsen Hall computer lab)
Tom Ray, 325-3526, 203-0703, Sutton Hall Room 210
http://www.ou.edu/cas/zoology/bioinformatics_course.htm

I. Introduction to Bioinformatics

 1  Aug 22  M   Lecture - Introduction

II. Unix Basics

 2  Aug 24  W   Lecture - Linux
 3  Aug 29  M   Lab - Linux

III. Genome Sequencing and Databases

 4  Aug 31  W   Lecture - Genome Sequencing, Phred, Phrap, Consed, Sequin
 5  Sep  7  W   Lecture - guest lecture: Jim White & Steve Kenton
 6  Sep 12  M   Lab - ACGT Tour

 7  Sep 14  W   Lecture - Assembly Process - The NCBI Data Model
 8  Sep 19  M   Lab - Data bases on the web

 9  Sep 21  W   Assisted Review
10  Sep 26  M   Exam - Linux, Phred, Phrap, Consed, Sequin, Databases

IV. Sequence Alignment

11  Sep 28  W   Lecture - Pairwise Alignment
12  Oct  3  M   Lab - Dotter, Align, Lalign

13  Oct  5  W   Lecture - Multiple Sequence Alignment
14  Oct 10  M   Lab - CLUSTAL, MEME

V. Database Searching for Similar Sequences

15  Oct 12  W   Lecture - Searching Databases to Match Sequences
16  Oct 17  M   Lab - FASTA, BLAST, SSEARCH,

17  Oct 19  W   Assisted Review
18  Oct 24  M   Exam - Dotter, Align, Clustal, Meme, Fasta, Ssearch, Blast
19  Oct 26  W   Lecture - Searching Databases to Match Patterns

VI. Gene Analysis

20  Oct 31  M   Lab - HMMER, MAST, PSI-BLAST
21  Nov  2  W   Lecture - Gene Prediction
22  Nov  7  M   Lab - Sim4, Genscan, GrailExp
23  Nov  9  W   Exam - HMMER, MAST, PSI-BLAST - Sim4, Genscan, GrailExp

VII. Protein Analysis

24  Nov 14  M   Lecture - Predicting Protein Structure - PREDATOR
25  Nov 16  w   Lecture - Protein Structure - CN3D, MMDB, VAST
26  Nov 21  M   Lecture - Microarrays - guest lecture: Tyrrell Conway

VIII. Phylogenetic Prediction

27  Nov 28  M   Lecture - Phylogenetic Prediction - Phylip
28  Nov 30  W   Exam - CN3D, MMDB, VAST, PREDATOR, Phylip
29  Dec  5  M   Lecture - Paup - guest lecture: Richard Broughton

IX. Introduction to Bioinformatics Programming

30  Dec  7  W   Lecture - Perl in Bioinformatics

IMPORTANT: This syllabus is tentative.  There will be changes.

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